Total Synthesis of terpenoids, Caribenol A and Artemisinin


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	2007年11月5日至7日，来自澳大利亚、美国、加拿大、日本、匈牙利、中国等国家的近百名农业科学家聚会中国杨凌，以“国际农业合作、创新与发展”为主题，就旱区农业与节水农业、高效畜牧业与动物疾病防控、食...
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2015

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Hongdong Hao

Department Chemie und Biochemie, Ludwig-Maximilians- Universität München

Caribenols A and B, both are norditerpenoids isolated from Pseudopterogorgia elisabethae. are active against Mycobacterium tuberculosis H₃₇Rv (61% and 94% growth inhibition at 64 -128 g/mL), have a potential to be a lead drug for anti-tuberculosis, their structure feature also caused interest by the synthetic community.

In the first part of this report, a detail synthetic study toward Caribenol A was reported including several failed route. We also give a introduction of synthetic work on Caribenol B.

In the second part, we will tell a story about how to achieve the synthesis of Artemisinin based on a very simple concept.

Total Synthesis of terpenoids, Caribenol A and Artemisinin

发布时间：2015-12-31 来源：

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